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Carcinoid tumors are neuroendocrine tumors typically arising in the gastrointestinal GI tract, most notably in the ileum, the last third of the small intestine, and the appendix, but may occur elsewhere in the body including the lungs, rectum, colon, pancreas, stomach, ovary, thymus, kidney, prostate, and breast. The term "carcinoid" usually implies a well-differentiated tumor with cells more like normal cells, slower growing, and therefore with less invasive malignant potential. Carcinoid syndrome is a disease defined by a constellation of symptoms, physical manifestations, and abnormal laboratory findings. Carcinoid syndrome is most often seen in patients who have an underlying primary carcinoid tumor arising from the ileum that became advanced, migrated to the lymph nodes, and then spread to the liver where metastatic tumors developed.
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Signs and Symptoms of Gastrointestinal Carcinoid Tumors
Carcinoid syndrome - Symptoms and causes - Mayo Clinic
If the tumor is discovered, it is usually when the appendix is removed for some other problem. Sometimes, the tumor blocks the opening between the appendix and the rest of the intestine and causes appendicitis. This leads to symptoms like fever, nausea, vomiting, and abdominal belly pain. If the tumor starts in the small intestine, it can cause the intestines to kink and be blocked for a while. This can cause cramps, belly pain, weight loss, fatigue, bloating, diarrhea, or nausea and vomiting, which might come and go. These symptoms can sometimes go on for years before the carcinoid tumor is found.
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NEJM Journal Watch
Skip to Content. Use the menu to see other pages. This type of tumor is usually found by a surgeon during an unrelated surgery or on x-rays for another condition. The signs and symptoms of carcinoid syndrome and carcinoid crisis, which are conditions that a GI tract NET can cause, are also described. If you are concerned about any changes you experience, please talk with your doctor.
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